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A New Nano-Spotting Tool for Reagent Delivery

05 FR GEFC 0BOI

 

 

 

Abstract
A French SME, specialised in nano-engineering and instrumentation, has developed a new nano-spotting tool. It is a microsystem designed to achieve nano-volume reagent delivery (nl or sub-nl range). The system performs reagent deposition on most types of chip substrates (glass, membranes, plastic and also at the bottom of microtiter plates). The company is looking for technical cooperation or marketing agreements with research laboratories or companies active in biotech, pharmacy, etc.

 

 

 

Description
A French SME that specialises in nano-engineering and nano-instrumentation has developed a new nano-spotting tool. It consists in a microsystem designed to achieve reagent nano-volume delivery from 0,5 to 1 nl. The system performs reagent deposition on most types of chip substrates including glass, membranes, plastic, and also at the bottom of microtiter plates.

This new product is based on micro-array contact printing technologies. Thanks to its miniaturisation, the system integrates a micro-reservoir and a micro-valve and it allows reproducible and homogeneous spotting of sub nano-volume as well as good optimisation of costly reagent volumes and experimentation time. Compatible with different protocols, it can handle various biological solutions such as DNA, RNA, proteins, and cells. The spotting is a new product and is targeting micro-array contact printing.

The system is designed and engineered to meet the needs of micro-array research and testing applications to overcome users constraints, e.g. spotting variability, cross-contamination, waste of precious samples, limited reliability of data and applications. The system is robust, flexible and ready for use. The nano-spotting tool covers a wide range of research applications in genomics, proteomics, cell biology, as well as industrial sectors.

The French company is able to provide also biochip preparation or manufacturing services to partners needing that kind of services.

Innovative Aspects:
- Integration of nanofluidic functionalities in mm size
- Feed-through washable to avoid contamination and carryover problems which are crucial in biological applications such as biochips
- Preservation of reagent from evaporation

Main Advantages:
- Adaptability to most commercial arrayers
- Reliability, spotting performance and precision
- Easy to use and flexible
- Compatibility with most biological reagents and process 

 

Development phase

Already on the market

 

Intellectual Property Rights

Patent(s) applied for but not yet granted

 

Collaboration details
Technical Co-operation, License agreement, Commercial Agreement with Technical Assistance

- Type of partner sought: Industry, research, laboratories
- Specific area of activity of the partner: Biotechnologies, pharmacy, cosmetic, medical

- Task to be performed: Partners willing to use the nano-spotting tool or to sell it. Co-development is also possible.
In case of commercial agreement with technical assistance, the French company could provide engineering & technical consultancy.

 

For more information
Anne-Marie VIEUX

 

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